The Manhyia Palace Museum was built around the old resting place of Otunfuo Agyeman Prempeh I and Otumufuo Sir Osei Agyeman Prempeh II, the 13th and 14th Kings of Asante kingdom. It was rehabilitated and became a museum in 1995. The building is of great historical interest and importance. It does not only comprise museum exhibits as the structure is also an exhibit.

The museum was officially launched on 12th of August, 1995 by Otumfuo Popku Ware II, the 15th King of Asante as part of the acts that marks the 50th year of his accession to Asikadwa. Tourists coming to the museum will also have the chance to explore video presentations describing the history and culture of Asante, alongside with notable examples of gold works.

It includes gold weights, bracelets, and pots for gold dust. Also there are the life sized effigies of the legendary Nana Yaa Asantewaa, Nana Prempeh I, and Queen of Ejisu who led the last wars.